Valacyclovir (generic for Valtrex) is a medication approved by the FDA to treat different types of herpes infections including HSV-1 and HSV-2. It is also used to treat shingles (herpes zoster), which is caused by the Varicella Zoster Virus (VZV). There are four different ways that herpes medications can be used to treat genital herpes (HSV-1 and HSV-2): 1. To Treat Or Abort An Outbreak When There Are Early Symptoms (Prodrome): For both genital and oral herpes, people can take medication when their specific prodrome tells them an outbreak is about to occur. The medication will stop an outbreak cold (often) and when it does not, it can shorten the outbreak and make it milder than it might have been otherwise. To Prevent Outbreaks When There Are No Symptoms But Outbreaks Are More Likely: Patients also learn the life circumstances or behaviors that lead to more outbreaks. 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