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    Metronidazole may also be prescribed to relieve inflammation of the intestinal tract. Because the drug can penetrate the blood-brain barrier and bone, it is sometimes used to treat infections of the central nervous system, bones, and teeth. Metronidazole’s mechanism of action is not fully understood. It may disrupt the ability of some microorganisms to make new genetic material. Its anti-inflammatory action within the gastrointestinal tract may be related to suppression of some parts of the immune system. Keep the oral, liquid form of metronidazole refrigerated and shake well before use. Tablets and capsules are to be kept in a tightly sealed container at room temperature and protected from heat and light. Metronidazole is an antibiotic that is used commonly to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is absorbed rapidly from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is used commonly with other antibiotics when it is used to treat mixed-bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins. It also is used to treat anaerobic bacterial infections. Metronidazole has immune-modulating activity and may be prescribed to treat inflammatory bowel disease.

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    It can also be used to treat infections of the urinary or genital tract, oral cavity, throat or skin caused by anaerobic bacteria susceptible to metronidazole. Do not use in case of hypersensitivity to the active substance or to any of the excipients. The product is suitable for use in both dogs and cats. Treatment of infections of the urogenital tract, oral cavity, throat and skin caused by obligate anaerobic bacteria (e.g. Due to the likely variability (time, geographical) in the occurrence of metronidazole resistant bacteria, bacteriological sampling and susceptibility testing are recommended. Contraindications Do not use in case of hepatic disorders. Whenever possible, the product should only be used based on susceptibility testing. Do not use in case of hypersensitivity to the active substance or to any of the excipients. Official, national and regional anitmicrobial policies should be taken into account when the veterinary medicinal product is used. Metrobactin 250 mg tablets for dogs and cats 1 tablet contains: Active substance: Metronidazole 250 mg Metrobactin 500 mg tablets for dogs and cats 1 tablet contains: Active substance: Metronidazole 500 mg Tablet. In very rare cases, neurological signs may occur especially afer prolonged treatment with metronidazole. Light brown with brown spots, round and convex flavoured tablet with a cross-shaped break line on one side. Dogs and cats Treatment of gastrointestinal tract infections caused by Giardia spp. Metronidazole has confirmed mutagenic and genotoxic properties in laboratory animals as well as in humans. Metronidazole is a confirmed carcinogen in laboratory animals and has possible carcinogenic effects in humans. Metronidazole is used to treat Giardia infections in dogs and cats. Giardia is a parasite that lives in the small intestine and can cause diarrhea. The organism can be found in contaminated soil, food, and water. Metronidazole can also be used to treat other parasites or anaerobic infections. Adverse effects reported in dogs Report any neurological side effects to your pet's veterinarian. It is important to finish the treatment course set by your pet's veterinarian. Your pet may appear better but may require continuing treatment - always give all the doses prescribed by the veterinarian.

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