Chloroquine phosphate dosage malaria prophylaxis

Discussion in 'Pharmacy Northwest Canada' started by Flegint, 02-Mar-2020.

  1. Fla$hKa New Member

    Chloroquine phosphate dosage malaria prophylaxis


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    An alternative to chloroquine for prophylaxis only in areas with chloroquine-sensitive malaria 310 mg base 400 mg salt orally, once/week 5 mg/kg base 6.5 mg/kg salt orally, once/week, up to a maximum adult dose of 310 mg base Prophylaxis of falciparum malaria in areas where resistance to chloroquine is moderate Child 1.7 mg chloroquine base/kg once daily always combined with proguanil Adult 100 mg chloroquine base once daily always combined with proguanil Travellers should start prophylaxis 24 hours before departure. Considerations when choosing a drug for malaria prophylaxis Recommendations for drugs to prevent malaria differ by country of travel and can be found in Malaria Information by Country. Recommended drugs for each country are listed in alphabetical order and have comparable efficacy in that country.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine phosphate dosage malaria prophylaxis

    DailyMed - CHLOROQUINE PHOSPHATE tablet, CHLOROQUINE sulfate or phosphate oral - Essential drugs

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  4. For individuals with significant risk factors daily dose of chloroquine phosphate greater than 2.3 mg/kg of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT.

    • CHLOROQUINE PHOSPHATE, USP - Food and Drug Administration.
    • CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria.
    • Chloroquine Phosphate Indications, Pharmacology, Dosage..

    Mar 16, 2020 The man said that doctors recommend taking 500 mg of chloroquine phosphate for eight days, and the WhatsApp message also included a photo of chloroquine phosphate tablets. The fraudulent claim was. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine dose for the treatment of uncomplicated Malaria 1000 mg 600 mg base on day 1, followed by 500 mg 300 mg base at 6, 24, and 48 hours after the first dose. Concomitant therapy with primaquine in patients with chloroquine-sensitive P.vivax and P.ovale is necessary.

     
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