Woman in grey hydroxychloroquine-induced hyperpigmentation

Discussion in 'Northwest Pharmacy' started by ua9aj, 10-Mar-2020.

  1. Astro"va New Member

    Woman in grey hydroxychloroquine-induced hyperpigmentation

    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

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    Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. A 48-year-old man with a long-standing history of systemic lupus erythematosus presented with a three-month history of mottled blue-grey hyperpigmentation on his face and on areas of previous bruising on his arms and legs Figure 11. There was no involvement of the mucous membrane or nails. His Background/Purpose To describe the clinical features and outcome of hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus SLE. Method This was a retrospective, monocentric SLE clinic, Pitié-Salpêtrière, Paris study of SLE patients with pigmented lesions considered to be related to hydroxychloroquine HCQ.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Woman in grey hydroxychloroquine-induced hyperpigmentation

    Skin Pigmentation with Hydroxychloroquine Plaquenil., Hydroxychloroquine-related skin discoloration CMAJ

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  3. The authors report the first case of a 47-year-old woman with acquired hemochromatosis in which hyperpigmentation of the upper eyelids was particularly enhanced. Case Report A 47-year-old disabled woman presented for a routine skin exam complaining of hyperpigmented areas on the face.

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    Hydroxychloroquine-related skin discoloration. Woman in grey Hydroxychloroquine-induced hyperpigmentation. clinical features and risk factors of hydroxychloroquine-induced pigmentation. Woman With Blue-Gray Palate and Nail Beds. Melikoglu MA, Melikoglu M, Gurbuz U, et al. Hydroxychloroquine-induced hyperpigmentation a case report. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B.

  4. GrainZ Moderator

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    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. QUINORIC 200MG FILM-COATED TABLETS Hydroxychloroquine Leaflet 2014 HYDROXYCHLOROQUINE SULFATE 200 MG FILM-COATED TABLETS
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