Chloroquine dosage adult

Discussion in 'Hydroxychloroquine' started by antaftcit, 03-Mar-2020.

  1. Steisy Guest

    Chloroquine dosage adult


    -After IV artesunate, for severe malaria (if other options are not available); if needed, as interim therapy for severe malaria until IV artesunate arrives (if other options are not available) -Current guidelines should be consulted for additional information. 250 mg orally once a week Comments: -This drug should be taken on the same day of each week, preferably after the main meal.

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    In adults, the loading dosage of chloroquine is 1000 mg. In children, the loading dose is about 16.7 mg per kg of body weight about 7.6 mg per pound of body weight, which can be divided into two doses taken six hours apart. Adults 1 g 600-mg base P. O. followed by 500 mg 300-mg base P. O. after 6 to 8 hours; then a single dose of 500 mg 300-mg base P. O. for next 2 days or 4 to 5 ml 160- to 200-mg base I. M. and repeated in 6 hours if needed; change to P. O. as soon as possible. Fourth dose 36 hours after first dose 8.3 mg chloroquine phosphate/kg 5 mg base/kg orally. Total dose 41.7 mg chloroquine phosphate/kg 25 mg base/kg in 3 days. Comments -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Use: For the prophylaxis of P falciparum and P vivax malaria infections, including prophylaxis of chloroquine-resistant strains of P falciparum US CDC Recommendations: 250 mg orally once a week Comments: -Recommended as prophylaxis in areas with mefloquine-sensitive malaria -Prophylaxis should begin at least 2 weeks before travel to malarious areas, continue during the stay, and then continue for 4 weeks after leaving these areas. -Prophylaxis should begin 1 week before arrival in an endemic area, continue during the stay, and then continue for 4 weeks after leaving the area.

    Chloroquine dosage adult

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  4. The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base and each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg base.

    • CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG.
    • Chloroquine Dosage Guide with Precautions -.
    • Hydroxychloroquine Dosage Guide with Precautions -.

    Adults weighing 60 kg or more. 1,000 mg 600 mg base PO, then 500 mg 300 mg base PO in 6 to 8 hours, then 500 mg 300 mg base PO once daily for 2 days. Total dose is 2.5 g chloroquine phosphate 1.5 g base in 3 days. The CDC recommends adding primaquine for P. vivax or P. ovale. Oct 01, 2018 Adults An initial dose of 1 g salt = 600 mg base followed by an additional 500 mg = 300 mg base after six to eight hours and a single dose of 500 mg = 300 mg base on each of two consecutive days. This represents a total dose of 2.5 g Chloroquine phosphate or 1.5 g base in three days. Adults—1000 milligrams mg once a day, taken for 2 days. This is followed by 500 mg once a day for at least 2 to 3 weeks. Children—Use and dose must be determined by your doctor. Missed Dose. If you miss a dose of this medicine, take it as soon as possible.

     
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    Quinolones and fluoroquinolones - Pharmacorama Quinolones and fluoroquinolones inhibit topoisomerase II, also called DNA-gyrase. Topoisomerase II, made up in Escherichia coli of an alpha subunit and two beta subunits, cut the two strands of DNA reducing their supercoiling and allowing their separation, necessary for replication and transcription.

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