This includes questioning the safety of topical products -- such as sunscreens -- over fear that they may cause birth defects. Haglund's syndrome is an inflammatory condition that could affect the area around your heel, where a small fluid-filled sac, called a bursa, allows the Achilles' tendon to slide smoothly over the bony ridge of your calcaneus (heel bone). Plaquenil and ocular toxicity Plaquenil cost increase Side effects of plaquenil on the eyes Can plaquenil raise your blood pressure Give antacids and laxatives at least 4 h before or after hydroxychloroquine. Store at 15°–30° C 59°–86° F unless otherwise directed. Adverse Effects 1% CNS Fatigue, vertigo, headache, mood or mental changes, anxiety, retinopathy, blurred vision, difficulty focusing. GI Anorexia, nausea, vomiting, diarrhea, abdominal cramps, weight. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. Aplastic anemia can be a temporary side effect of these treatments. Exposure to toxic chemicals. Toxic chemicals, such as some used in pesticides and insecticides, and benzene, an ingredient in gasoline, have been linked to aplastic anemia. Although not all of these side effects may occur, if they do occur they may need medical attention. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Hydroxychloroquine side effects aplastic anemia Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Plaquenil What is hydroxychloroquine and shortness of breathAralen phosphate cost Adverse hematologic effects including neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia have been rarely associated with 4-aminoquinolines. Therapy with 4-aminoquinolines should be administered cautiously in patients with preexisting bone marrow suppression. Hydroxychloroquine Disease Interactions -. Aplastic anemia - Symptoms and causes - Mayo Clinic. Hydroxychloroquine Davis's Drug Guide for Rehabilitation.. What are the side effects and risks of hydroxychloroquine? Ocular side effects. Hydroxychloroquine can cause irreversible retinal toxicity, resulting in bilateral bull’s eye retinopathy, but is regarded as less toxic to the retina than chloroquine and it does not cause the corneal deposits seen with chloroquine therapy. All treatments can cause side-effects. However, the type and severity will vary between individuals, depending on the type of treatment used and how an individual responds to it. In general, more intensive treatment is associated with more severe side effects. It is important to report any symptoms Summary Aplastic anemia is found among people who take Plaquenil, especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months, also take medication Prednisone, and have Paroxysmal nocturnal haemoglobinuria.