Additionally, another exception occurred while executing the custom error page for the first exception. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Plaquenil pill side effect Comprar aralen en méxico My last retina scan shows some thinning of the retina so I am being scheduled with a specialist for further testing and I have been told there is a good possibility I will have to stop taking Plaquenil. I know my sight is most important but it makes me nervous that I may have to change medications. Plaquenil has been a miracle drug for me. You can read more about this new type of retinal imaging procedure here. The take away is this if you are taking this medication, talk to your doctor about the use of Plaquenil in your particular circumstance, discuss the dose prescribed, and get your eyes checked for Plaquenil related retinal toxicity on a regular basis. Typically, cases of HCQ toxicity may demonstrate parafoveal thinning and loss of the ellipsoid zone, with preservation of the foveal architecture — creating the “flying saucer” shape Figures 1 and 2. Advanced cases may present with loss of the ellipsoid zone in the foveal area and also widespread diffuse thinning of the outer retinal. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Retinal thinning in plaquenil toxicity Selective Thinning of the Perifoveal Inner Retina as an Early., Reasonably Well Rheumatology News Retinal Hazards of Long Term Plaquenil Hydroxychloroquine interactions with famotidine In addition to retinal thinning and outer retinal degeneration, HCQ appears to induce choroidal thinning, particularly at the level of the choriocapillaris. These findings will broaden our understanding on ocular toxicity of HCQ and clinical evaluation for the toxicity. Choroidal Thinning Associated With Hydroxychloroquine Retinopathy.. Retinal Physician - Hydroxychloroquine Maculopathy An.. Rx Side Effects New Plaquenil Guidelines and More - American.. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Retinal photograph showing classic “bull’s eye” retinopathy of hydroxychloroquine toxicity, which represents atrophy of the retinal pigment epithelium. This is a relatively late change, and good screening can detect toxicity before any bull’s eye is visible.