I need it because my Sjogren's Syndrome and Fibromyalgia have been out of control. I have a new diagnosis of osteoarthritis and moderate welling to my lower extrimities. Plaquenil knee weakness Stopped plaquenil now symptoms have returned When I was having the recurring bouts of pericarditis my rheumie told me that having sjogrens along with lupus was a big factor in the pericarditis. I'm not sure if this was based on clinical studies or just his own experience, but the materials I got from the Sjogrens Foundation when I was diagnosed do mention pericarditis as a common. Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Lupus pericarditis is the most common type of heart disease affecting those with lupus. The trigger, it seems, is antigen-antibody complexes produced during active lupus. These antigen-antibody complexes, also known as immune complexes, can cause inflammation within the pericardium. Thanks, Ashley Hi Ashley, I have been on plaquinel for 2 years now and feel like it has been the best thing for me. What does the Plaquinel do to the symptoms and progression of Sjogrens? Plaquenil for pericarditis Will you have Pericarditis with Plaquenil - eHealthMe, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine plaquenil withdrawal symptomsPlaquenil and proceduresHydroxychloroquine reviews uk I have had lupus for 6 years now and within the past 6 months I have had 5 bouts with pericarditis.first it was treated with prednisone and NSAIDS but then after the 3rd bout I was put on Plaquenil. After 4 weeks on it, I developed itching and burning all over my body so my rheum. took me off of it but the itching and burning continued. Lupus and Pericarditis - Treato. How Lupus Can Lead to Pericarditis. Pericarditis Diagnosis & Treatment Webchat Drs. Klein.. Plaquenil hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. It will help with mild/moderate joint pain, but is usually given with other drugs for better pain relief. It works well on the more systemic side effects of RA e.g. pericarditis, pleuritis, fevers, etc. which is why Plaq is also used with lupus patients. In a recent preliminary report, 21 colchicine was tested as the initial treatment for the first episode of acute pericarditis in order to prevent recurrences. This unblinded, randomised trial involved 60 patients who received either 800 mg/6–8 hours of aspirin for 7–10 days with gradual tapering over 2–3 weeks.