Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Plaquenil and liver transplant Plaquenil autoimmune neutropenia User Reviews for Hydroxychloroquine. Also known as Plaquenil, Quineprox The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Plaquenil can cause loss of appetite and I agree that losing weight at this rate and suffering diarrhea is not healthy and might mean you become ill nourished and dehydrated. I suggest lowering the dose, going back to the original, until your tum has settled down then very gradually increasing it to give your body the maximum chance to adjust. There is a small risk that hydroxychloroquine can damage your retina part of the eye, and this increases with long-term use and higher dosage. Your doctor will advise you on a safe dose to take according to your weight, and you will need to have regular monitoring of your eyes. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Weight loss taking hydroxychloroquine Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Plaquenil & weight loss Lupus Forums at The Lupus Site Signs of retinal damage from plaquenilPlaquenil lupus reviews By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Rx Side Effects New Plaquenil Guidelines and More - American.. Hydroxychloroquine Side-effects, uses, time to work. Will you have Weight loss with Hydroxychloroquine sulfate.. Find reviews for Hydroxychloroquine from other patients. Learn from their experiences about effectiveness, side effects and cost. Dismiss this notification PatientsLikeMe would like to remind you that your browser is out of date and many features of the website may not function as expected. The Hopkins team seems to have found a workable middle ground – weight-based dosing up to a maximum of 400 mg/day, which is considered safe in a lean person of about 136 pounds. Three months after being prescribed hydroxychloroquine, however, just 56% of the patients were at a therapeutic level of 500 ng/mL or more. The linear regression analysis revealed that the duration of treatment was significantly associated with a decrease in Bacteroidetes P = 0.0001, Firmicutes P = 0.002, and total bacteria P 0.00001. Abnormal weight gain is a side effect of long-term doxycycline and hydroxychloroquine treatment.