Please review the following URL and make sure that it is spelled correctly. Description: An exception occurred while processing your request. Can plaquenil be taken long term Effects of hydroxychloroquine on taste Digoxin chloroquine Chloroquine injection dosage Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Safe use of Plaquenil. In our eye clinic we frequently see patients who need to be screened because they have been prescribed hydroxychloroquine Plaquenil and have concerns, so I wanted to write a short article summarizing the necessity and purpose of proper eye screening in these individuals. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. These changes, if they are going to occur, happen slowly over a long period of time. Your eye care provider can examine the macula and detect subtle changes before you begin to notice any symptoms of problems. A 45-year-old black female presented with no ocular or visual complaints. However, her medical history was significant for a recent diagnosis of lupus. Additionally, another exception occurred while executing the custom error page for the first exception. Color vision changes associated with plaquenil toxicity Plaquenil Side Effects on Your Eyes and Vision, Plaquenil hydroxychloroquine and eye screening Jitander Dudee Plaquenil and liver toxicity The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. My Take on New Ocular Screening Guidelines for Plaquenil.. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Hydroxychloroquine toxicity - EyeWiki. Visual complaints are primarily associated with central vision loss, and visual field or color vision anomalies. 38-40 There is one report of progressive hydroxychloroquine toxicity mimicking low-tension glaucoma after discontinuation in a patient with a cumulative dose of 2,200,000 mg. 41 It is also reported that there is a diminished ERG associated with hydroxychloroquine toxicity. Doses ≥ 5 mg/kg/day real weight of hydroxychloroquine 2.3 mg/kg/day of chloroquine are associated with higher risk of toxicity. Doses lower than 5 mg/kg/day have low risk 1% for the first 5 years, and below 2% between 5-10 years of use. The longer you use. Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment. If a person is going to be treated long-term with Plaquenil, they need to have a thorough dilated eye exam with best corrected visual acuity, central visual field, color vision, and dilated examination of the retina.