Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Coppolino quarantine chloroquine Should you take plaquenil in the am or pm Is chloroquine safe in first trimester of pregnancy Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Blood monitoring can be discontinued in primary care after 2 years on treatment Hydroxychloroquine Any time No primary care blood monitoring required. Ophthalmology monitoring is the responsibility of the specialist, but the patient must be advised to report any visual disturbances immediately to the GP / Optometrist. Annual screening is recommended in all patients who have taken hydroxychloroquine for greater than 5 years; Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Hydroxychloroquine monitoring requirements Hydroxychloroquine Uses, Dosage & Side Effects -, Summary of Monitoring Requirements for Medicines used in. Plaquenil caterats Hydroxychloroquine and in patients with psoriasis since it appears to. Inform patients of the long term monitoring requirements Inform the GP of the information provided to the patient To review the patient at agreed intervals and copy any relevant HYDROXYCHLOROQUINE Shared Care Guideline V1. HYDROXYCHLOROQUINE SULFATE Drug BNF content published.. Disease-modifying Antirheumatic Drugs DMARDs. Patient.. Hydroxychloroquine monitoring requirements. What monitoring is required for hydroxychloroquine? No routine laboratory monitoring is required for hydroxychloroquine. For people on long-term therapy 5 years or more, an annual eye assessment ideally including optical coherence tomography should be carried out. Find an Ophthalmologist. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. The amount of monitoring with hydroxychloroquine varies from centre to centre. More frequent surveillance is needed if laboratory values are abnormal or with high-risk patients. The patient's full blood count, renal function, and liver function should be examined at baseline, then checked periodically.