Plaquenil was the only drug for me which gave me instantaneous better saliva flow improved my depression within a week. The downside: I got a severe allergic reaction, eye trouble, enormous chills, constipation, weight gain and anorgasmia... Plaquenil synthesist Hydroxychloroquine actavis Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Dosage While in some cases, lower doses of NSAIDS are effective, in rheumatoid arthritis and other forms of inflammatory arthritis a higher dose is often required to decrease inflammation. A lower dosage can initially be used if inflammation is mild, if mechanical pain is the major problem. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people. Pilocarpine, thyroid meds, 25mg quetiapine, 1% testosterone. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('02), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). So please anyone, is there something else which can 'kill the bugs' inside me? DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('02), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Hydroxychloroquine alternative Hydroxychloroquine - Wikipedia, Rheumatoid Arthritis Treatment Options Johns Hopkins. Hydroxychloroquine sulfate tablets ipPlaquenil side effects heart I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Natural" alternative to Plaquenil. - HealthBoards. Compare Plaquenil vs Chloroquine -. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. I originally took Plaquenil Sanofi but this brand is now discontinued. The generic form of this, on my prescription, gives me serious digestion and stomach upsets to a point I spent months trying to figure out what I thought was irritable bowel syndrome. Has anyone found a good alternative UK brand that doesn't create this side affect. Apr 02, 2010 there are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. i researched these drugs before i made my decision and so for myself i started on the enbril and boy what a difference. Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another.