Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Dark palate hydroxychloroquine Hydroxychloroquine sulfate 200 mg dosage What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. I’ve been on plaquenil for almost 3 years and I still have diarrhea and to a lesser extent heartburn and nausea sometimes. The first year or two I was on plaquenil I didn’t have a normal bowel movement for as long as I could remember and was constantly nauseous and could barely eat. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil diarrhea nausea Common and Rare Side Effects for Plaquenil Oral, Plaquenil and. diarrhea! rheumatoid Porqué tomar plaquenil y no otros medicamentos biologicosChloroquine malaria chemical formulaDoxycycline and plaquenil together How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil and diarrhea - Answers on HealthTap. Nausea nervousness nightmares sensation of spinning shakiness and unsteady walk uncontrolled eye movements unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Side Effects. Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Ginny, I had some very minor diarrhea, nausea, cramping for about a week when I started Plaquenil. Everyone is different, but for me, taking the med about 15 min. after eating, rather than before or with a meal, makes things much easier on my stomach, even for just Advil. I do think you should let your rheumy know.