While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. When should you take plaquenil Plaquenil half-life Chloroquine clathrin Jun 11, 2013 Study Raises Questions about Sjogren's and Plaquenil. Generic plaquenil does not work for me. I did breastfeed for 5.5 years so apparently this doesn't raise. Hi - I have just had the same problem and my consultant has recommended that the next step is to take methotrexate via injection; and if this doesn't work after 6 months he is going to try another drug which I can't remember the name of will find out and post. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. What if plaquenil doesn t work Taking Plaquenil for Rheumatoid Arthritis, Methotrexate not working so what next? Hi everyone as. - NRAS Plaquenil multiple sclerosisHow does plaquenil work in the bodyHigh risk medication icd 10 plaquenilPlaquenil toxicity octPlaquenil 400 mg daily cost The dizziness upon standing may be postural hypotension. The brain is not getting enough oxygen because the body is not appropriately shuttling blood up there and gravity pulls it to your toes. Those with adrenal insufficiency have this, and increasing salt load or if that doesn't work, taking medication for it helps. What step comes after plaquenil?. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Does Plaquenil actually work for you? autoimmunity. May 23, 2016 Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Plaquenil does help with some of the symptoms of Lupus, but it does take a few weeks to start helping. It's most important role is to inhibit progression of the disease -- I'm really surprised you haven't been on it ever since the Lupus was diagnosed. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.