Severe malaria should be treated with intravenous (IV) antimalarial medications. As a result, CDC is providing IV artesunate for the treatment of all severe malaria cases. With the discontinuation of IV quinidine, IV artesunate is now the first-line drug for treatment of severe malaria in the United States. Plaquenil photosensitivity rash Plaquenil 200 mg price greece Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons. It is used in the treatment and prophylaxis of malaria due to susceptible strain of Plasmodium falciparum, P. ovale, P. vivax and P. malariae. ADMINISTRATION. Chloroquine Phosphate Injection is administered by slow intravenous route. The intramuscular route is used where intravenous administration is not possible. Parenteral chloroquine may be administered safely by simply giving smaller, more-frequent doses than are currently used or, in the case of iv administration, by using continuous infusion. PMID 3543146 It is unknown when IV artesunate will receive FDA approval, as this process requires an interested drug company to submit a new drug application to FDA. IV artesunate is the recommended World Health Organization (WHO) first-line treatment for severe malaria but is neither FDA-approved nor commercially available in the United States. Chloroquine injection intravenous Chloroquine Oral, Intramuscular Advanced Patient. -, Nelbquine Chloroquine Phosphate Injection - Boditreat Medication reaction to plaquenilPlaquenil and early pregnancyPlaquenil eye toxicityPlaquenil eyes side effects Oct 20, 2012 Quinine and chloroquine may cause potentially lethal hypotension if given by intravenous injection. Chloroquine is extensively distributed with an enormous total apparent volume of distribution Vd more than 100 L/kg, and a terminal elimination half-life of 1 to 2 months. Pharmacokinetics of Quinine, Chloroquine and Amodiaquine.. Parenteral chloroquine for treating falciparum malaria.. Chloroquine Injection Uses, Side Effects, Interactions.. SCOTT V. Single intravenous injections of chloroquine in the treatment of falciparum malaria toxic and immediate therapeutic effects in 110 cases. Am J Trop Med Hyg 1950; 3. Djimdé A, Doumbo OK, Cortese JF, et al. A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med 2001; 37. Aug 19, 2014 Mice injected daily with chloroquine showed slower growth and less lung metastasis of subcutaneous melanoma xenografts. However, chloroquine did not suppress the invasion of cultured cancer cells into Matrigel, and lung colonization was not reduced by exposure of cancer cells to chloroquine prior to intravenous injection in mice. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite.