I'm currently on plaquenil 400mg daily and methotrexate 25mg weekly`many thanks in advance Did you tell the prescriber that you were on MTX? MTX should not be taken with any penicillin type drug. Hydroxychloroquine intoxication Mefloquine lariam and chloroquine Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. The FDA hasn’t approved minocycline for rheumatoid arthritis, but it’s been studied and used for decades. Most research seems to indicate good results. If you’re interested in this treatment. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. You can cut or crush this oral tablet. Take each. I'm honestly just curious because I've taken penicillin abx many times while on methotrexate... You also need to be very careful taking MTX with any type of chest infection and should not take it at all if you have pneumonia. I just finished pharmacology in nursing school, and also take methotrexate, and I've never heard that it shouldn't be taken with penicillin antibiotics - do you have any resources? Can you take antibiotics with plaquenil Stopping Plaquenil and Cellcept when on Antibiotics, Minocycline for Rheumatoid Arthritis An Antibiotic Protocol Plaquenil et soleilAralen retail price Plaquenil may increase the level of cyclosporine in your blood, which can be quite dangerous. If you take these two medications together, your healthcare provider may need to monitor your cyclosporine levels and adjust your cyclosporine dosage as necessary. Drugs That Can Interfere With Plaquenil - Antibiotics Home Page. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil and Sulfa Allergies" Lupus Community - Support Group. Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. The drug may be used to treat a type of blood disease called porphyria cutanea tarda. Hi i am on antibiotics for a chest infection and got a bad cold, my asthma as flared up to. i heard somewhere i should either be careful or not take my meds while on amoxicillin antibiotics, any ideas? i'm currently on plaquenil 400mg daily and methotrexate 25mg weekly` many thanks in advance This could increase your risk for side effects or decrease the effectiveness of the medicines. To help prevent potentially negative Plaquenil drug interactions, tell your healthcare provider about all other medications you are taking before starting Plaquenil.