The antiviral medications available to treat genital herpes are acyclovir, famciclovir (Famvir), and valacyclovir (Valtrex). Acyclovir has the most data on the safety of use in pregnancy. A registry of over 1000 pregnant women who were exposed to acyclovir during early pregnancy suggests that acyclovir is probably safe as there were no increases in birth defects. Before the acyclovir I was on 500 mg of Valtrex once daily but my insurance made me change to acyclovir. The Valtrex was working well and so was the acyclovir (I was having outbreaks about every other month) until about 2 months ago. When you say HIV is a long shot risk (a very long shot) how concerned should I be? I assume you mean that it is unlikely that I have HIV? as you may know, such infections are more common in diabetics than people without diabetes. None of the antiherpes drugs (acyclovir, valacyclovir, famciclovir) will interfere with your diabetes drugs. If not, get a prescription right away; it will help speed healing of your herpes. Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, which is converted to aciclovir in a persons body. Common adverse drug reactions (≥1% of patients) associated with valaciclovir therapy are the same as for aciclovir, its active metabolite, and include: nausea, vomiting, diarrhea and headache. Infrequent adverse effects (0.1–1% of patients) include: agitation, vertigo, confusion, dizziness, edema, arthralgia, sore throat, constipation, abdominal pain, rash, weakness and/or renal impairment. Rare adverse effects ( Valaciclovir belongs to a family of molecules first described and patented by Paolo Cornaglia Ferraris in 1982 (patents EP0077460 A2, CA1258149A1, DE3273785D1, EP0077460A3, EP0077460B1, US4567182). Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10–20%). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.
Vectavir is a brand name for penciclovir, an anti-herpes cream. Zovirax is a brand name for acyclovir, an anti-herpes drug that is available as a pill or a cream. In general, pills are much more effective for herpes than creams. Read more Vectavir (penciclovir) is a cream for herpes. Zovirax (acyclovir) is available both as a cream and pills to be taken by mouth. Neither cream works very well; if herpes treatment is needed, pills are always best. Some experts feel the newer agents and especially valcyclovir are better, but each can help. In other words, Vectavir and Zovirax creams are both poor treatments, but Zovirax pills usually are very effective. The choice depends on several factors - how often someone wants to or can take the med, for example. Read more I'm assuming you're talking about oral Valtrex (valacyclovir) and zovirax (not zovirax cream). The main issue is usually cost and whether one or the other is covered by insurance. Both are effective, but Valtrex (valacyclovir) is more convenient, because it doesn't have to be taken as frequently. © 2005, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
About 6 months ago I was tested positive for HSV-2. I have had several outbreaks since then, but they were all pretty minor (1-2 sores). I was taking Valtrex daily for about a month and a half, but I developed what appeared to be cystic acne the whole time I was on it. As soon as I stopped, my skin cleared up, but I had another outbreak, so I went back on it and my skin started to break out again. I've never read anything about that being a side effect, but it was the only explanation. I talked to my doctor about this and she told me to try acyclovir instead. My main concern is to lower the risk of infection in my new partner. I haven't yet told him that I have herpes, but when I do I want to be able to say that the risk of transmission is very low (when combining daily suppressive drugs and condoms). It comes in the form of a tablet you take by mouth. Valacyclovir is available as a brand-name drug called Valtrex. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. This drug may be used as part of a combination therapy. This means you may need to take it with other medications. Valacyclovir is used to treat viral infections caused by a group of viruses called herpes simplex viruses. These infections include oral and genital herpes, shingles, and chickenpox.
Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Mirabile on acyclovir vs famciclovir Vectavir is a brand name for penciclovir, an anti-herpes cream. Zovirax is a brand name for acyclovir, an anti-herpes drug that is available as a pill or a cream. In general, pills are much more effective for herpes than creams. Valtrex vs valacyclovir. Common Questions and Answers about Valtrex vs valacyclovir. Most Ob's treat there patients with HSV-2 with acyclovir usually not valacyclovir during the last month of pregnancy, which is effective in preventing outbreaks that can require CS, and also probably reduces the risk of transmission to the baby from.