Generic Name: Metformin (met-for´min) Brand Name: Glucophage, Glucophage XR Classifications: hormone and synthetic substitute; antidiabetic; biguanide Pregnancy Category: B Availability : 500 mg, 850 mg tab-lets; 500 mg sustained release Actions Biguanide oral hypoglycemic agent. Unlike sulfonylureas, biguanides do not stimulate the release of insulin from the beta cells of the pancreas. Mechanism of action is thought to be due to both increasing the binding of insulin to its receptor and potentiating insulin action. Therapeutic effects Improves tissue sensitivity to insulin, increases glucose transport into skeletal muscles and fat, and suppresses gluconeogenesis and hepatic production of glucose, thus lowering blood glucose levels. with meals, may increase by 500–850 mg/d every 1–3 wk (max: 2550 mg/d); or start with 500 mg sustained release with p.m. Uses: Treatment of type 2 diabetes mellitus in patients not controlled with diet alone. Contraindications Hypersensitivity to metformin; renal, hepatic, or cardiopulmonary insufficiency; alcoholism; concurrent infection. Route & Dosage Type 2 Diabetes Mellitus adult: PO Start with 500 mg q.d. This is not a list of all drugs or health problems that interact with this medicine (metformin tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (metformin tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. However, many people have no side effects or only have minor side effects.
Just as health comprises a variety of physical and mental states, so do disease and disability, which are affected by environmental factors, genetic predisposition, disease agents, and lifestyle choices. Health, disease, and disability are dynamic processes which begin before individuals realize they are affected. Disease prevention relies on anticipatory actions that can be categorized as primal, primary, secondary, and tertiary prevention. According to estimates made by the World Health Organization (WHO), about 55 million people died worldwide in 2011, two thirds of this group from non-communicable diseases, including cancer, diabetes, and chronic cardiovascular and lung diseases. Preventive healthcare is especially important given the worldwide rise in prevalence of chronic diseases and deaths from these diseases. It is recommended that adults and children aim to visit their doctor for regular check-ups, even if they feel healthy, to perform disease screening, identify risk factors for disease, discuss tips for a healthy and balanced lifestyle, stay up to date with immunizations and boosters, and maintain a good relationship with a healthcare provider. Some common disease screenings include checking for hypertension (high blood pressure), hyperglycemia (high blood sugar, a risk factor for diabetes mellitus), hypercholesterolemia (high blood cholesterol), screening for colon cancer, depression, HIV and other common types of sexually transmitted disease such as chlamydia, syphilis, and gonorrhea, mammography (to screen for breast cancer), colorectal cancer screening, a Pap test (to check for cervical cancer), and screening for osteoporosis. They worked at the Harvard and Columbia University Schools of Public Health, respectively, and later expanded the levels to include secondary and tertiary prevention. Genetic testing can also be performed to screen for mutations that cause genetic disorders or predisposition to certain diseases such as breast or ovarian cancer. though the terms primary, secondary, and tertiary prevention are still in use today. Health care providers can use the mnemonic “Meals on Wheels” (see below) to identify common treatable causes of unintentional weight loss. In the frail elderly, even small amounts of weight loss can have negative consequences, and all elderly patients are encouraged to maintain their nutrition and weight over the years as even voluntary weight loss has been associated with increased risk of death and hip fracture.3 Complications of unintentional weight loss include anemia, decreased cognition and quality of life, edema, falls, hospitalizations, hip fractures, infections, nursing home placement, osteoporosis, and pressure ulcers.1-3 Common Causes of Unintended Weight Loss Causes of unintentional weight loss can be divided into three main categories: • physiological (eg, diseases, cancer, dental problems, pain); • psychological (eg, depression, dementia); and • socioeconomic (eg, isolation, financial). 10 Unintentional weight loss, defined as a loss of 5% of body weight in one month or 10% in six months, is of significant concern in older adults.1,2 It’s a predictor of mortality, with 9% to 38% of older adults dying within one to 2 1/2 years of onset3 and the risk increasing four times with a 5% weight loss in one month. Elderly patients experiencing weight loss should be screened for depression (eg, Geriatric Depression Scale), as the incidence of depression is high among these patients in both community and nursing home settings. 3,4 There’s a possible link between rapid weight loss and the onset of Alzheimer’s disease, with one study finding that twice as many patients with Alzheimer’s disease experienced a weight loss of 5% or greater compared with the study’s control patients. Screening for Alzheimer’s disease or dementia in elderly patients with unintended weight loss using a tool such as the Mini-Mental State Exam or Clock Drawing Test may help with earlier identification earlier of the condition and allow for the consideration of available treatments, such as acetylcholinesterase inhibitors (eg, Aricept, Exelon) and/or memantine (Namenda), to potentially slow cognitive decline. Medication side effects (see Table 1 below) often contribute to weight loss because of side effects such as anorexia, dry mouth, taste or smell disturbances, swallowing difficulties, and nausea or vomiting.3 A retrospective chart review in a 718-bed long term care facility found that more than 75% of the 41 patients with recent weight loss had received at least one medication known to potentially contribute to weight loss.5 Also, when health care providers had reviewed for possible causes of the weight loss, no changes in medication therapy had been attempted to evaluate the medications as an underlying cause.
Une fois les produits finis et le rendez-vous pour l’installation planifié, nous voici rendus à l’étape de l’installation des portes et fenêtres. Nos spécialistes certifiés vous expliqueront le déroulement des travaux afin que vous puissiez comprendre et suivre toutes les étapes du processus. Nos professionnels effectuent l’installation de vos portes et fenêtres dans un environnement sécuritaire pour votre famille et respectent les plus hauts standards de l’industrie. Nous travaillons de pair avec vous pour nous assurer que les produits que nous vous proposons répondent à vos besoins, vos attentes et votre budget. Nos experts s’assurent de vous proposer un devis précis, qui correspond à l’architecture de votre demeure. Nos spécialistes sont certifiés pour tous les types de travaux de livraison et d’installation de portes et fenêtres, et respectent les normes strictes établies par l’industrie de la construction. Nos experts vous offrent une installation minutieuse pour vous assurer une tranquillité d’esprit. There will be a chart available for this at Nrsng.com/1. Our database of Nursing Podcasts is key to us achieving that mission. to help you understand and feel confident with nursing pharmacology. Today I just want to talk about a couple of the different methods of oxygen delivery systems that we have available for our patients. . achieve this goal we are relentlessly creating resources that will help you study, pass, and feel confident. Find our why our shows are rated “Best Nursing Podcasts” year after year. In this show we have taken the 140 most commonly tested and prescribed medications and created a short 5-10 minute episode that covers the details of the medication. Here is a list of our shows and how they can help you on your journey to RN. With the Med Master Podcast you no longer have an excuse to struggle with pharmacology. Listen Now Understanding labs is so crucial to being an effective nurse. Many nursing students and nurses struggle with making the connection between a patients lab results and their condition. To address this problem we created the lab values podcast and ton of other resources on lab values.
Metformin. 2 July, 2004. VOL 101, ISSUE 40, PAGE NO 37. and customised email alerts; Bite-size learning through NT Self-assessment and NT Journal club. Une fois les produits finis et le rendez-vous pour l’installation planifié, nous voici rendus à l’étape de l’installation des portes et fenêtres.