My basic executive summary is that it worked for me, and I'm glad I took it. Here're my thoughts, just in case someone else is depressed and has been mulling the use of an antidepressant. From the middle of March, 2004, to the summer of 2008, I took daily 10mg doses of the prescription anti-depressant "Lexapro". There's a whole chemistry system in the brain related to the production and subsequent "reuptake" (dunno why they don't just say "uptake") of the neurotransmitter seratonin. I don't understand the chemical cycle very well, but what I gather is that the brain creates seratonin and uses it in neural functions, but that a portion of the seratonin created is simply sucked back up, broken apart, and not used. Deficiencies in available seratonin are tied in several medical studies to depression, difficulty sleeping, weight gain, aggression, and difficulty focusing. The suggestion is that some people who are depressed may simply have brains that "reuptake" too much seratonin relative to the amount their brains create. Over the past 30 years, medical science has learned the importance of brain chemistry. Previously, depression was thought to result from problems of living, with a psychiatrist's couch the best remedy. It is now clear that most victims of depression have something wrong with their neurotransmitters—decisive brain chemicals such as serotonin, dopamine, norepinepherine, and the endorphins, all of which have a powerful influence on intelligence, personality, and moods. Most psychiatrists resort to powerful brain-altering drugs, in an attempt to help their patients. However, individual responses to drug medications are extremely variable and this therapy is more of an art than a science, with medications administered on a crude trial-and-error basis. There is no doubt that prozac, zoloft, risperdal, and other medications provide benefits to many patients. However, the benefits are usually quite incomplete and these medications often have serious side effects, such as blunting of personality, movement disorders, and fatigue.
In a placebo-controlled, double-blind, randomized study of the comparative abuse liability of ZOLOFT, alprazolam, and d-amphetamine in humans, ZOLOFT did not produce the positive subjective effects indicative of abuse potential, such as euphoria or drug liking, that were observed with the other two drugs. Contact Pfizer Safety to report an adverse event, side effect or concern about the quality of a Pfizer product: (800) 438-1985 You may also contact the U. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns at 1-800-FDA-1088 or gov/Med Watch If you are looking for information about Pfizer studies currently recruiting new patients in your area, you can begin your search on our website. For questions about a Pfizer Clinical Trial, call (800) 718-1021 or email Pfizer Rx Pathways® connects eligible patients, regardless of their insurance status, to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings. For more information, please call (844) 989-7284 or visit Eligible patients can register for valuable savings offers for nearly 40 brand name medications. Also known as: Zoloft The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."Wouldn’t recommend this at all. It seemed like the first few days I didn’t really notice much except I would wake up in the mornings feeing slightly nauseous. Then about a month or so in I started getting tremors in my upper body and I could sense them coming on a few hours before waking up every single morning and I try so hard to just sleep through them. Then eventually I’ll toss and turn and no matter what position I sleep in it hurts my body. Then I’ll wake up to horrible pain in my back, neck and shoulders. I wouldn’t take it ever again and I’m only on 25mg so I’m hoping to get off really soon! ""Started with 50mg for 4 months but felt like it wasn't doing anything.
Feb 22, 2016. "When you really fall in love, there's a lot of dopamine and euphoria. and four months off Zoloft, I recognized that my newly-paranoid feelings. How a life was changed for the worse in the blink of an eye by a prescription for sertraline and the problems that have followed.