This means your healthcare provider has given it to you as part of a treatment plan. Prednisone is part of a group of drugs called corticosteroids (often called "steroids"). Other steroid drugs include prednisolone, hydrocortisone, and methylprednisolone. Prednisone can be given in different ways, including pill, injection, and inhaled. It is usually given as a pill when used after a kidney transplant, or for certain kidney disorders. Steroid drugs, such as prednisone, work by lowering the activity of the immune system. Steroids work by slowing your body’s response to disease or injury. Prednisone can help lower certain immune-related symptoms, including inflammation and swelling. Prednisone is a man made anti-inflammatory with anti-inflammatory and immunomodulating properties derived from cortisone (corticosteroid). Corticosteroids are not the same as anabolic steroids. In contrast to anabolic steroids (used by “bodybuilders”), prednisone (corticosteroid) is used in inflammatory conditions for their anti–inflammatory effects. Prednisone has a rapid onset of action, and profoundly affect many parts of the immune system as well as most other body systems. Prednisone is biologically inert and converted to prednisolone in your liver. Prednisone is a glucocorticoid receptor agonist (activator). Prednisone is first metabolized in your liver to its active form, prednisolone.
Prednisone and prednisolone are glucocorticoids which reduce inflammation and inhibit immune system responses. They are several times stronger than the stress hormone “cortisol” which is produced naturally in a dog’s adrenal glands and are often used for treating Addison’s disease in which your dog’s glands do not produce enough cortisol on their own. Because they suppress the immune system they are also effective in the treatment of allergies and are sometimes used as a follow-up to epinephrine when dogs have suffered anphylactic shock (a very severe allergic reaction). In terms of antiinflammatory effects, prednisolone is 4x more potent than hydrocortisone. It is not to be confused with methylprednisolone, which is a slightly more powerful variant of the drug. What’s the difference between prednisone and prednisolone? Prednisone is actually a “precursor” to prednisolone. Anabolic steroids are very useful in treating patients with severe burns that require assistance regenerating tissue, patients infected with the HIV virus who have lost significant weight, patients who have intestinal diseases that inhibit their ability to absorb food, and cancer patients who are losing weight and have appetite loss as a result of chemotherapy. Prednisone is sometimes part of the treatment plan for various types of lymphomas, leukemia, and bronchitis. It is also sometimes used to suppress the immune system of individuals who have organ transplants to lessen the chances of the body rejecting the new organ. The drug has significant medical utility, and it is not a drug that is highly sought after by bodybuilders, athletes, etc., because it is not an anabolic steroid. Prednisone is typically taken orally, but corticosteroids like prednisone can be used in topical medications. The side effect profile of prednisone is relatively benign, and few individuals experience side effects. According to the Food and Drug Administration (FDA), the most common side effects of prednisone include: Although there are side effects associated with the use of any medication, prednisone is typically well tolerated in most individuals.
Table of contents. Prednisone and asthma. Side effects. Alternatives. Speaking to a doctor. Outlook. Prednisone is a prescription medication that belongs to a class of drugs known as steroids or corticosteroids. What is Prednisone? Whether your dog has inflammation, arthritis or endocrine disorders such as Addison’s disease, your veterinarian might havePrednisone for dogs is often used in veterinary practices to treat a range of diseases that are related to inflammation and inflammatory responses.