Metformin (met-FOR-min) is a antihyperglycemic drug used to treat type 2 diabetes and sometimes polycystic ovary syndrome (PCOS). It is the first-line medication for type 2 diabetes in the UK. Metformin is a biguanide, part of a family of compounds that share a similar chemical structure. It is the only biguanide available to the public as a medicine. Metformin acts in three ways: For women with PCOS, metformin stimulates ovulation even if you don’t have diabetes (as it lowers insulin and blood sugar levels). Metformin comes as two different types of tablet, an oral solution and oral powder. The two types of tablet are: 1) Standard-release tablets. The immediate-release tablet is available as the brand-name drug Glucophage. Metformin oral tablet comes in two forms: immediate-release and extended-release. The extended-release tablet is available as the brand-name drugs Glucophage XR, Fortamet, and Glumetza. Both tablet forms are also available as generic drugs. Generics usually cost less than brand-name versions. In some cases, they may not be available in all strengths or forms as brand-name drugs. Metformin oral tablets are used to treat high blood sugar levels caused by type 2 diabetes.
Metformin is classified as a biguanide is used as a first-line drug treatment for type 2 diabetes, and also for insulin resistance, PCOS, and even cancer. It is the most commonly prescribed anti-diabetic medication in the world [R]. Metformin adjusts cellular energy consumption by targeting the liver, preventing it from creating more sugar (glucose), and inhibiting a hormone (glucagon) responsible for increasing blood sugar levels. It also decreases the absorption of glucose in the gut and increases insulin sensitivity [R, R]. The effect of metformin on blood sugar levels can be attributed to AMPK, an enzyme that controls the production and storage of energy in cells by regulating when muscle cells should increase their sugar uptake from the blood [R]. Recently, attention has shifted to non-AMPK mechanisms, often involving mitochondria, the parts of cells responsible for energy production [R]. Type 2 diabetes coexists with insulin resistance and patients develop extremely high blood sugar levels. FREE unlimited standard delivery (3 to 5 business days) to any mailing address within the 50 U. Also includes discounts on non-standard shipping and shipping outside the U.
Find patient medical information for Metformin Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Metformin The Benefits of the Diabetes Drug 3 60% 1 vote One of the most common preventable diseases in the Western world, Type-II diabetes hosts a variety of side effects that can make anyone’s day-to-day seem impossible to get through.