As a bachelor's-prepared registered nurse with more than 15 years of diversified experience, Juliet Wilkinson innerves our health-conscious population through expert articles. She is a motivated professional who believes that preventive care is the first step towards health and well-being. View Full Profile Try to lose the mindset that tamoxifen is responsible for the weight gain. There is a distinct possibility that any weight gained could be due to the chemotherapy preceding the tamoxifen. Placebo testing has not demonstrated that tamoxifen causes weight gain. Mayo suggests that calorie counting is an effective weight-loss strategy. The oncologist should be able to provide a healthy daily calorie goal for you -- stick to it. Tamoxifen is an oral drug that blocks the effects of estrogen, the hormone that promotes the growth of some types of breast cancer. Tamoxifen has been used for many years to prevent recurrences of estrogen-receptor-positive breast tumors – that is, tumors that need estrogen to grow. In 1998, results of a study involving more than 13,000 women showed that tamoxifen can also lower the risk of breast cancer among healthy women, cutting the anticipated number of cases by 49 percent. However, until recently, no study looked at tamoxifen’s effects on overall survival. The latest on tamoxifen comes from an analysis showing that the drug doesn’t change the life expectancy of many of the women who take it to prevent breast cancer. This is because of serious side effects: increased risks of cataracts, deep vein thromboses, endometrial cancer and uterine sarcoma, and strokes. In addition, women who do develop breast cancer while taking tamoxifen preventively are more likely to have estrogen-receptor-negative tumors, which are more aggressive and deadly.
Tamoxifen Nolvadex prescribed for the prevention and treatment of breast cancer in men and women, and occasionally, to stimulate ovulation in women. Common side effects include depression, nausea. Your extra weight may hang around and increase after chemotherapy if you also take hormonal therapy tamoxifen or an aromatase inhibitor.